1.0FactCheckVaccine.comhttps://factcheckvaccine.comFCVhttps://factcheckvaccine.com/author/factcheckvaccine/rich600338<blockquote class="wp-embedded-content"><a href="https://factcheckvaccine.com/2021/06/breaking-news-novavax-traditional-vaccine-brings-imminent-competition-to-the-genetic-based-vaccines-currently-under-eua-june-14-2021/">Breaking News Novavax’ Traditional Vaccine Brings Imminent Competition to the Genetic-based Vaccines Currently Under EUA [June 14, 2021]</a></blockquote> <script type='text/javascript'> <!--//--><![CDATA[//><!-- /*! This file is auto-generated */ !function(c,d){"use strict";var e=!1,n=!1;if(d.querySelector)if(c.addEventListener)e=!0;if(c.wp=c.wp||{},!c.wp.receiveEmbedMessage)if(c.wp.receiveEmbedMessage=function(e){var t=e.data;if(t)if(t.secret||t.message||t.value)if(!/[^a-zA-Z0-9]/.test(t.secret)){for(var r,a,i,s=d.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),n=d.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),o=0;o<n.length;o++)n[o].style.display="none";for(o=0;o<s.length;o++)if(r=s[o],e.source===r.contentWindow){if(r.removeAttribute("style"),"height"===t.message){if(1e3<(i=parseInt(t.value,10)))i=1e3;else if(~~i<200)i=200;r.height=i}if("link"===t.message)if(a=d.createElement("a"),i=d.createElement("a"),a.href=r.getAttribute("src"),i.href=t.value,i.host===a.host)if(d.activeElement===r)c.top.location.href=t.value}}},e)c.addEventListener("message",c.wp.receiveEmbedMessage,!1),d.addEventListener("DOMContentLoaded",t,!1),c.addEventListener("load",t,!1);function t(){if(!n){n=!0;for(var e,t,r=-1!==navigator.appVersion.indexOf("MSIE 10"),a=!!navigator.userAgent.match(/Trident.*rv:11\./),i=d.querySelectorAll("iframe.wp-embedded-content"),s=0;s<i.length;s++){if(!(e=i[s]).getAttribute("data-secret"))t=Math.random().toString(36).substr(2,10),e.src+="#?secret="+t,e.setAttribute("data-secret",t);if(r||a)(t=e.cloneNode(!0)).removeAttribute("security"),e.parentNode.replaceChild(t,e)}}}}(window,document); //--><!]]> </script><iframe sandbox="allow-scripts" security="restricted" src="https://factcheckvaccine.com/2021/06/breaking-news-novavax-traditional-vaccine-brings-imminent-competition-to-the-genetic-based-vaccines-currently-under-eua-june-14-2021/embed/" width="600" height="338" title="“Breaking News Novavax’ Traditional Vaccine Brings Imminent Competition to the Genetic-based Vaccines Currently Under EUA [June 14, 2021]” — FactCheckVaccine.com" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe>https://factcheckvaccine.com/wp-content/uploads/2021/06/Breaking-News-Novavax-Traditional-Vaccine-Brings-Imminent-Competition-to-the-Genetic-based-Vaccines-Currently-Under-EUA.png1328606Also referred to by the tradename “Coronavax”, this prefusion protein vaccine candidate is based on the company’s proprietary nanoparticle technology known as Matrix-M, an adjuvant that boosts immune response, thus triggering greater amounts of SARS-CoV-2 neutralizing antibodies. The candidate product is based on an engineered baculovirus (an insect virus that does not infect animals) which includes a modified SARS-CoV-2 spike protein gene. This recombinant insect virus then infects and introduces Sf9 moth cells, which then causes the spike protein to be produced by these cells and display the protein on their cell membranes (see the Precision Vaccinations report: here). The production process then involves the harvesting and assembly of these cell membranes displaying the spike protein “onto a synthetic lipid nanoparticle about 50 nanometers across each displaying up to 14 spike proteins”, again, as summarized in the Precision Vaccinations report. Using proprietary formulation methods, Novavax then combines this vaccine candidate with their patented saponin-based Matrix-M adjuvant which stimulates the migration and activation of antigen-presenting cells at the injection site, while boosting antigen presentation via local lymph nodes which all works to augment immune response, thus aiding the immunized person to produce sufficient antibodies against SARS-Cov-2.